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Can biotherapy such as high dose interleukin 2 cause chemobrain? The 6 cycles of HD IL2 were administered with many other drugs (not chemo) such as dopamine, ritalin, demerol, ativan, etc. I was in ICU and the hospital for much of Jan-July receiving the courses of IL2.

If biotherapy did not cause my "chemo" brain, could 2 doses of revimid and dtic chemotreatments be contributing to my confusion, memory loss, etc.? I had those 2 cycles last Nov. and Dec.

Thank you.


Posted: 01 Aug 2006 10:18 AM
Originally Posted: 01 Aug 2006 10:19 AM
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Biotherapy is even worse than chemotherapy for causing chemobrain. We think that chemobrain may be due sometimes to an inflammatory response, involving the production of cytokines. IL-2 and interferon are cytokines, and cause a lot of alterations in the brain, including inducing other cytokines, causing a stress hormone cascade, and altering neurotransmitters.

Christina Meyers, Ph.D.

Posted: 03 Aug 2006 02:59 PM
Originally Posted: 03 Aug 2006 03:00 PM
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