I was a patient at MD Anderson about a year ago seeking a second opinion. I started my bout with bladder cancer about 2 1/2 years ago with a 6 cm stage 1 grade 3 renal tumor, which resulted in a nephrouterectomy. After a year of being "clear", I had multiple recurrences in the bladder that were removed with three TURTB's about 3 months apart (the last one was at MD Anderson). The pathology of the last two TURTB's was grade 3 and grade 2.
With my 'prescription' from MD Anderson, and my local Urologist's orders, I started BCG/Interferon instillations in December 2008 as follows: once a week for 6 weeks, then once a month for 3 months, and now once every 3 months for up to 2 years, depending on my tolerance and the success. Thus far I have had 10 treatments with no recurrence.
This may not be a question that you can answer, but I am wondering if one can be 'cured' by BCG or if I am in a holding pattern?
BCG is the most effective therapy we have to reduce recurrence and prevent progression. Many individuals are cured by BCG, and it is possible that the tumors that recurred in the bladder were seeded by your renal tumor. Maintenance therapy improves the results of therapy but the regimen you are following is not the regimen that we commonly use.Generally we recommend a 6 week induction and then administer weekly BCG for 3 weeks at 3 and 6 months and then every six months for a total of three years. This regimen has given the best results but has not been compared head to head with the maintenace regimen you are following.
Posted: 12 Feb 2010 03:25 PM Originally Posted: 12 Feb 2010 03:26 PM