Mario R. Capecchi, Ph.D. will visit Houston and MD Anderson on Friday, January 14, 2011 to accept the Mike Hogg Award and deliver a lecture. Hosted by the MD Anderson Alumni & Faculty Association, the Award & Lecture are underwritten by the Mike Hogg Fund.
Dr. Capecchi, an HHMI Investigator is Professor and Chair in the Department of Genetics, the University of Utah School of Medicine.
A 2007 Nobel Laureate in Physiology and Medicine with Oliver Smithies and Martin Evans, Capecchi is best known for his pioneering work on the development of gene targeting in mouse embryo-derived stem (ES) cells. This technology allows scientists to create mice with mutations in any desired gene. The power of this technology is that the investigator chooses both which gene to mutate and how to mutate it. The investigator has virtually complete freedom on how to manipulate the DNA sequences in the genome of living mice. This allows scientists to evaluate in detail the function of any gene during the development or post-developmental phase of the mouse. His research interests include the molecular genetic analysis of early mouse development, neural development in mammals, production of murine models of human genetic diseases, gene therapy, homologous recombination and programmed genomic rearrangements in the mouse.
The Mike Hogg Lectureship is the most prestigious at MD Anderson Cancer Center. The annual Mike Hogg lecture series began during Dr. R. Lee Clark's tenure and the initial organizer was Dr. Clark Griffin. Nobel Prize winners who are still active in research are honored and invited to deliver a lecture as part of the award.
The Mike Hogg Fund is dedicated to the support of medical research and education to providing "medicine and hospital care and attention for worthy and deserving persons" within the state of Texas. The fund was established in 1955 by Alice Nicholson Hanszen in memory of her first husband.