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New Melanoma Drugs Raise Hopes, But More Choices Needed

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After years of failure in the treatment of advanced melanoma, two new drugs have emerged that help patients with one of the most deadly and difficult-to-treat cancers.

The experimental drug PLX4032 targets a specific genetic mutation found in the tumors of about half of all patients.  Ipilimumab,  an antibody that stimulates an immune system attack on melanoma, recently was approved by the U.S. Food and Drug Administration for treatment of the disease.

It's an optimistic time, says Michael Davies, M.D., Ph.D., an assistant professor in MD Anderson's Department of Melanoma, as scientific findings translate into new treatments. However, the new drugs don't help everyone and melanoma eventually resists them, often in less than a year's time.

Development of new drugs is crucial, Davies notes. Today, he chairs a seminar titled Novel Targets in Melanoma Research, which brings leaders in the field together to share new approaches at the American Association for Cancer Research 102nd Annual meeting. In video interviews, Davies discussed progress against melanoma and what still needs to be done.

3 Comments

My 43 year old Daughter, found out she has stage 4 Melanoma Cancer, the dermatologist removed the mole and had it tested.
What type of treatment is mainly used for this stage


She has a consultation Nov. 5, 2013 at MD Anderson downtown.
As her mother I worry, just was wondering how many of this type of cancer are are cured.
Kristy lives in Katy

Thank you..Pat Bizzell Bryan,Texas

I'm so sorry to hear about your daughter, Pat. Please let us know if she needs anything. If you call 1-877-632-6789 they can answer any questions you might have and provide you with more information. Your family is in our thoughts and prayers.

Thank you for your prayers

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