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Recently by Oliver Bogler Ph.D

The mission of M. D. Anderson's Odyssey Program is to support the best among the newest generation of cancer researchers here and encourage them to explore novel areas of clinical, translational, basic or population-based cancer research. To fulfill this mission, the Odyssey Program supports them and their research during their post-doctoral training, a critical career phase during which scientists first develop independence and a funding track record.

Odyssey Fellowships are given annually, with a start date of Sept. 1, following an open call for applicants and a rigorous peer-review process. This round we had 41 applications from 26 departments and were able to support three new fellows, about 7%, making the Odyssey Program's competition one of the toughest. You can compare this to the National Institutes of Health payline, which even in the toughest times has stayed above 10%.

The three awardees who will join the Odyssey Program in 2009 are:

• Dr. Calley Hirsch from Dr. Sharon Dent's lab (Department of Genetics): "The Role of Gcn5 in Mouse Embryonic Stem Cells"

• Dr. Marites Melancon from Dr. Jason Stafford's lab (Department of Imaging Physics): "Targeted Nanoshell-Based Agents for MRI-Guided Thermal Ablation of Head and Neck Cancer"

• Dr. Sofie Claerhout from Dr. Gordon Mills' lab (Department of Systems Biology): "Tumor Dormancy and Autophagy -- Implications for Breast Cancer"

I want to thank the Odyssey Program Advisory Committee for their hard work in scoring these applications.

The Odyssey Program is supported by  endowments from the Theodore N. Law Award For Scientific Achievement, Houston Endowment, Inc. Award for Scientific Achievement, H-E-B Award for Scientific Achievement, Kimberly-Clark Foundation Award for Scientific Achievement, Cockrell Foundation Award for Scientific Achievement, The Kimberly Clark Fund for New and Innovative Research. Recently the program has received generous support from the CFP Foundation and the Arnold Family Foundation.


A very exciting Symposium on Cellular Energy, Metabolism and Cancer was recently held at M. D. Anderson. The focus of the meeting was the role of alterations in metabolism in cancer, a topic that has been debated since first proposed by Dr. Otto Warburg ( http://en.wikipedia.org/wiki/Otto_Heinrich_Warburg ) in the early 20th century.

With the tremendous advances in genomics, proteomics and delineation of regulatory pathways, cancer biologists are taking a second close look at metabolism and finding that the switch to non-oxidative glycolysis is a hallmark of cancer.

A high point of the meeting was a keynote lecture by Dr. Craig Thompson from the Abramson Cancer Center of the University of Pennsylvania, who gave a broad overview of the field and set the stage for ensuing discussions. Another keynote at the end of the meeting by Dr. Ron Evans of the Salk Institute described some elegant work on how agents targeting nuclear receptors can be used to mimic exercise in mice -- fitness in a bottle.

The Bertner Award Prize was received by Dr. Lew Cantley of Harvard Medical School, whose work on PI3 kinase signaling has been a major force in the cancer field for years, and in the context of cellular energy is showing new, important directions. Three poster prizes also were presented.

The program was very multidisciplinary, including population sciences and therapeutic development. It was planned by the meeting's three co-chairs: Drs. Michele Forman, Cheryl Walker and Dihua Yu of M. D. Anderson.

A new facet of the symposium is that we recorded 18 of the 24 presentations, which are being posted on M. D. Anderson's iTunes University site.

 So, if you didn't get a chance to attend, you can catch the great science on your computer or MP3 player.

Give it a look or listen and let us know what you think.

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